Camptothecin (CPT) is a cytotoxic quino line alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used as a cancer treatment in Traditional Chinese Medicine. CPT showed remarkable anticancer activity in preliminary clinical trials but also low solubility and (high) adverse drug reaction. Because of these disadvantages synthetic and medicinal chemists have developed numerous syntheses of Camptothecin and various derivatives to increase the benefits of the chemical, with good results. Two CPT analogues have been approved and are used in cancer chemotherapy today, topotecan and irinotecan.
 

Product Name	Camptotheca Acuminata Extract
Botanical Source	Camptotheca Acuminata Decne
Used Part	Nut
Specification	98%  Camptothecin
Appearance	Light yellow crystalline powder
CAS NO.	7689-03-4
Test Method	HPLC
Extraction type	Solvent Extraction
Molecular Formula	C20H16N2O4
Molecular Weight	348.36
Grade	Pharmaceutical and food grade
Shelf life	2 years

Functions : 
 

1. Anti tumor effect.

2. Camptothecin can inhibit the proliferation of fibroblasts both in vivo and in vitro.

3. In addition, camptothecin has obvious inhibitory effect on herpesvirus.

4. In vivo, camptothecin is mainly excreted from bile and urine.

5. Camptothecin can induce chromosome aberration and is toxic.

6. Treatment of esophageal cancer, cardiac cancer.

7. Treatment of gastric cancer.

8. Treatment of primary liver cancer.

9. Treatment of psoriasis.

10. Treatment of skin warts.

1. Applied in the functional food field;
 

Hunan E.K Herb Co.,Ltd. founded in 2010, is a modern high-tech enterprise committed to plant functionality, the extraction and purification of active ingredients.Based on the construction of a high starting point, the company    has the domestic leading plant extract production line, is a refined production workshop with nearly 3000 square meters and nearly 20 mu of standardized crude lifting production workshop of large-scale production enterprises,  its core technology in the leading position in the domestic peers.E.K Herb with advanced production equipment & high-tech research and development level, characterized by high quality product quality, on the basis of integrity service consciousness and high level of service attitude, constantly launch new products, improve the enterprise platform, improve the corporate image, serve the society, just to create greater social value and economic benefits.

E.K Herb mainly features high purity products,such as Chlorogenic acid 98%, Ursolic acid 98%,Rosmarinic acid 98%,Carnosic acid 95% ,Amygdalin 98%, Dihydromyricetin 98%, Resveratrol 98%, EGCG 95%,, and personalized product demand, we use technical advantages, and strong research and development ability, to provide product customization and research and development outsourcing services, to meet the needs of different customers.The scope of products covers chemical industry, medicine, food, cosmetics and other fields, in the past ten years, E.K Herb has always uphold the spirit of ingenuity, to ensure the quality, with first-class quality second-rate prices, specifications, fast and thoughtful service by the majority of users.And applied for the five invention patents of "high purity green raw acid preparation process" ,"high purity lycopene preparation process", "High purity Rosemary acid preparation process", "High purity Ursolic acid preparation process", "High purity Amygdalin preparation process",and successfully passed the QS, 1S09001 and other certification.

E.K Herb adheres to the spirit of excellence and continuous innovation, and strives for the development and take-off of the plant extract industry!We will always be with the strictest product safety standards, the best product quality, the most intimate service level, wholeheartedly to serve you!

Office & Factory

Exhibition 

E.K Herb Team Building