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Hirudin is one of the most active components extracted from leech and its salivary gland. It is a small protein (polypeptide) composed of 65-66 amino acids. Leeches are rich in hirudin. Hirudin has a strong inhibitory effect on thrombin, which is the strongest natural specific inhibitor of thrombin. Hirudin has a strong effect of inhibiting blood coagulation and antithrombotic, and has a broad application prospect in clinical treatment and prevention of various thrombosis.
| English name | Leech extract |
| Active ingredients | Hirudin |
| Specification | 99%min hirudin powder |
| Use Part | Whole body |
| Appearance | White Powder |
| CAS No | 113274-56-9 |
| Molecular formula | C66H93N13O25 |
Hirudin Leech Extract(also called Leech Hirudin Powder) is the most significant active constituents, is dry leech extract and its salivary glands, and is a kind of small molecule protein (polypeptide) which comprised of 65-66 amino acid.
Hirudin Leech Extract is rich in hirudin, hirudin has a strong inhibitory effect on thrombin, is the strongest thrombin natural specific inhibitors.
Funtions :
1. Hirudin extract is a very promising kind of anticoagulant medicine.
2. Hirudin extract can be used to treat various thrombus diseases, especially the treatment of venous thrombosis and diffuse blood vessel coagulation.
3. Hirudin extract can also play a role in the treatment of tumor. It can prevent the metastasis of tumor cells, and has been proved to be effective in tumors such as fibrosarcoma, osteosarcoma, angiosarcoma, melanoma and leukemia.
4.It is a naturally occurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property.
5.It can prevent or dissolve the formation of clots and thrombi (i.e. it has a thrombolytic activity), and has therapeutic value in blood coagulation disorders, in the treatment of skin hematomas and of superficial varicose veins.
Applications :
1. Hirudin extract is a very promising kind of anticoagulant medicine.
2. Hirudin extract can be used to treat various thrombus diseases, especially the treatment of venous thrombosis and diffuse blood vessel coagulation.
3. Hirudin extract can also play a role in the treatment of tumor. It can prevent the metastasis of tumor cells, and has been proved to be effective in tumors such as fibrosarcoma, osteosarcoma, angiosarcoma, melanoma and leukemia.
Item | Specification | Result |
Assay | 99% | 99.68% |
Appearance | White Powder | conforms |
Odor | Characteristic | conforms |
Taste | Characteristic | conforms |
Particle Size | NLT 100% Through 80 mesh | conforms |
Loss on Drying | <2.0% | 0.45% |
Heavy metals | ||
Total Heavy Metals | ≤10ppm | conforms |
Arsenic | ≤3ppm | conforms |
Lead | ≤3ppm | conforms |
Microbiological Tests | ||
Total Plate Count | ≤1000cfu/g | conforms |
Total Yeast & Mold | ≤100cfu/g | conforms |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
E.K Herb mainly features high purity products,such as Chlorogenic acid 98%, Ursolic acid 98%,Rosmarinic acid 98%,Carnosic acid 95% ,Amygdalin 98%, Dihydromyricetin 98%, Resveratrol 98%, EGCG 95%,, and personalized product demand, we use technical advantages, and strong research and development ability, to provide product customization and research and development outsourcing services, to meet the needs of different customers.The scope of products covers chemical industry, medicine, food, cosmetics and other fields, in the past ten years, E.K Herb has always uphold the spirit of ingenuity, to ensure the quality, with first-class quality second-rate prices, specifications, fast and thoughtful service by the majority of users.And applied for the five invention patents of "high purity green raw acid preparation process" ,"high purity lycopene preparation process", "High purity Rosemary acid preparation process", "High purity Ursolic acid preparation process", "High purity Amygdalin preparation process",and successfully passed the QS, 1S09001 and other certification.
E.K Herb adheres to the spirit of excellence and continuous innovation, strives for the develop and booms of the plant extract industry!
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Packing & Shipping
Packing
* Delivery Time: Around 3-5 workdays after your payment.
* Package: In fiber-drums with two plastic bags inside.
* Net Weight: 25kgs/drum,Gross Weight: 28kgs/Drum
* Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
* Storage: Stored in dry and cool place, keep away from strong light and heat.
* Shelf Life: Two years when properly stored.
shipping
* DHL Express, FEDEX and EMS for quantity less than 50KG, usually called as DDU service.
* Sea shipping for quantity over 300KG; and air shipping is available for 50KG above.
* For high value products, please select air shipping and DHL express for safe.
* Please confirm if you can make the clearance when goods reach your customs before placing an order. For buyers from Mexico, Turkey, Italy, Romania, Russia, and other remote area.
A: The extract is a concentrated powder form of raw material. The herb extract's procedure flow is wash, extraction, concentration, purification, drying, grinding, sieving, package. The herb powder is just a powder form of the herb. The procedure flow is wash, drying, grinding, sieving, package.
Q2: What's the extract solvent used in the procedure?
A: The extract solvent is always depending on the active ingredient in the raw material, regulation and customers' requirement. The solvents mostly used for extraction are water and ethanol. Even the solvent other than water used in the procedure, the solvent residue in the extract product also can conform with ICH Q3CR5.
Q3: Is there any other ingredient used in the product?
A: It depends. For product which is hard to be dried, we need to add some maltodextrin into the extraction solution before drying. The maltodextrin we used is food-class carrier, from non-GMO corn. We can share customer with the ingredient composition table.
Q4: How to make sure the quality of the product?
A: Firstly, every batch finish product must be tested and qualified before delivery. We can send a specification sheet or CoA for confirmation. The HPLC chromatography graph also can be provided. Secondly, we can provide pre-ship sample to customer for quality confirmation.
Q5: Can you develop a new product for us?
A: Yes, we can. We have independent R&D dept, who is able to update the procedure parameters of our main products and develop the procedure of new product. For more information, please contact us directly.
Q6: Can you offer this in capsules or tablets as well?
A: Yes, we have related equipment for preparation of finish product, like tablet, capsule and granule. Kindly contact with us for details.
Q7: What is the MOQ?
A: For most of the products we already have in stock, the MOQ is 1kg. If the product is a new specification and need to be produced from raw material, the MOQ depends.
Q8: Is there any discount?
A: Yes, for larger quantity or better payment period, we can support with better price.
Q9: How about delivery time?
A: For most products, the product can be sent out from factory in 5days. If we don't have inventory, the product need to produced from raw material, the ordinary period is 20-25days.
Q10: How do you treat with quality complaint?
A: We will always be responsible for the quality of our products. If there's a complaint, we will first assist customers to solve the most direct needs.
Secondly, we have SOP for quality complaint. QA will investigate the problem, after that we'll give customer a timely feedback about the cause of the quality issue and related precautions for this problem.
