Audited Supplier
Frazer-Adapalene
Yes
Customized
GMP, HSE, ISO 9001, USP, BP
Elderly, Children, Adult
White Powder
>99%
Feed Grade, Food Grade, Medicine Grade
White Powder
106685-40-9
2 Years
HPLC
Powder
Store Cool Dry Place
C28h28o3
267.24
Xi'an Frazer Biotech Co., Ltd.
Foil Bag
99%
China
Product Description
Fast Shipping High Quality Cosmetic CAS 106685-40-9 Adapalene Powder
Product Description
 | What is Adapalene?Adapalene is a second-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions.[1] It is effective against acne conditions where comedones are predominant |
Application & Function of Adapalene
Adapalene is a Retinoic acid analogs.
Adapalene is an agonist of RARβ, and RARγ receptor.
Adapalene inhibits cell proliferation and inducing apoptosis in colorectal cancer cells in vitro. Adapalene gel is an effective medication for treatment of acne.
Specification of Analysis
Adapalene is an agonist of RARβ, and RARγ receptor.
Adapalene inhibits cell proliferation and inducing apoptosis in colorectal cancer cells in vitro. Adapalene gel is an effective medication for treatment of acne.
Specification of Analysis
| Analysis Item | Indexes |
| Characteristics | White or almost white crystalline powder |
| Identification | IR |
| Solubility | Practically insoluble in water and ethanol, sparingly soluble in te'trahydrofuran. |
| Appearance of solution | Solution must be clear and color NMT BY6 of EP |
| Heavy metals | ≤20ppm |
| Loss on drying | ≤0.5% |
| Sulfated ash | ≤0.1% |
| Related substances | Impurity A:≤0.3% ImpurityD: ≤0.2% Impurity C:≤0.15% Unknown impurity:≤0.1% Total impurity: ≤0.5% |
| Residue solvents | Te'trahydrofuran:≤720ppm Acetic acid:≤5000ppm M'ethanol:≤3000ppm N,N-dimethyl formamide:≤880ppm |
| Assay(on dried basis) | 98.0%-102.0% |
