Audited Supplier
Product Name: 2,3-Dimercaptosuccinic Acid/Dimercaptosuccinic Acid
Specification:98%
Appearance: White Powder
Test method: HPLC
Function
2,3-Dimercaptosuccinic Acid Powder is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of 2,3-Dimercaptosuccinic Acid is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. Dimercaptosuccinic Acid can cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.
Another application for 2,3-Dimercaptosuccinic Acid is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. Dimercaptosuccinic Acid is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a 2,3-Dimercaptosuccinic Acid challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, 2,3-Dimercaptosuccinic Acid share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.
The relative activities of a series of novel monoalkyl esters of meso-2,3-dimercaptosuccinic acid (2,3-Dimercaptosuccinic Acid) have been examined as agents for the mobilization of cadmium, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound 2,3-Dimercaptosuccinic Acid.
Application
Dimercaptosuccinic acid is a medication used to treat lead, mercury, and arsenic poisoning.
Dimercaptosuccinic acid is in the chelating agent family of medications. It works by binding with lead and a number of other heavy metals allowing them to leave the body in the urine.
Technical Specification:
| Items: | Requirements | Results |
| Appearance: | White crystalline powder | White crystalline powder |
| Identification | ||
| HPLC | The principal spot obtained with test solution corresponds in position, appearance ,and intensity with that obtained from reference solution. | Conforms |
| Residue on ignition | ≤0.5% | 0.32% |
| Loss on drying | ≤ 0.3% | 0.05% |
| Melting Pint | 190~194°C | 192~194°C |
| PH | 2.5~3.0 | 2.5 |
| Residual on Ignition | ||
| Iron(Fe) | ≤10ppm | <10ppm |
| Heavy metal | ≤ 10ppm | <10ppm |
| Pb : | <1 ppm | Complies |
| Cadmium(Cd) : | <0.5 ppm | 0.3ppm |
| As : | <10ppm | Complies |
| Hg: | < 1 ppm | Negative |
| DMSO content | ≤0.01% | 0 |
| Assay | ≥98% | 99.20% |
| Conclusion: | The product conforms to USP36. | |
Delivery: Sea/Air Shipping & International Express
Shipping Time:15 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 35cm (Diameter)*51cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
1.Free sample
2.Owning cultivation base as 100% Natural material stable source.
3.Manufacturer direct supply, Powerful R&D team and advanced test center
4.Leading plant extract manufacturer in China.
5.No excuse return of goods
6.OEM & ODM is available
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
Q4: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q5: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer.
In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment
