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               How do retatrutide receptor agonists work?

glucagon-like peptide-1

Glucagon-like peptide-1 (GLP-1) is a gut peptide horm produced by our body after eating. This hormone plays many roles and is primarily known for its role in regulating food intake and hunger.
GLP-1 promotes insuln secretion from the pancreas and reduces glucose release from the liver. In addition to lowering blood sugar levels, GLP-1 also produces slow gastric emptying. Food travels slower through the digestive system and remains in the stomach longer. This will make you eat faster when you eat, and you'll stay satisfied longer. GLP-1 also targets the brain's hunger center, reducing appetite. These two GLP-1 effects make you feel less hungry, acting like an appetite suppressant.



 

glucose-dependent insulnotropic peptide

Like GLP-1, glucose-dependent insulnotropic polypeptide (GIP) is part of a family of hormones called incretins. Therefore, the actions of both peptide hormons are very similar. This hormone is produced in the small intestine after we eat and helps lower blood sugar levels after eating. This hormone causes slow gastric emptying and decreased appetite. It targets the brain and digestive system, so the stomach is one of the best places to inject it for weight loss.



 

glucagon

Glucagon is another hormone that plays a crucial role in blood sugar management.
How does glucagon help with weight loss? Our bodies store excess glucose from the food we eat as glycogen and fat. When we don't eat carbs for a few hours, glucagon goes to work trying to produce glucose. This can happen when we sleep, eat a low-calorie diet, or practice the benefits of fasting on an hourly basis. First, glucagon breaks down glycogen, but after these stores are depleted, it breaks down our fat stores, converting them into fuel.



 

                 Among other things: Glucagon binds to GLP-1 and GIP resulting in increased energy expenditure. Your total energy expenditure is the number of calories you burn while doing any type of physical activity and the work your body does to perform important functions like breathing or digestion. Higher levels of energy expenditure mean your body will burn more fat.

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