Sterile Water for Injection Ampoule 5ml 10ml 50ml 100ml 500ml

1. Overview

Sterile Water for Injection (SWFI) is a sterile, non-pyrogenic, and distilled water preparation used as a diluent for reconstituting or dissolving medications for injection. It contains no antimicrobial agents or added substances.

2. Composition

• Active Ingredient: Sterile, non-pyrogenic water
• pH Range: Typically 5.0 to 7.0
• Osmolarity: Hypotonic (0 mOsm/L)

3. Uses & Indications

• Diluent for Medications: Used to dissolve or dilute drugs before IV, IM, or subcutaneous administration.
• Irrigation Solution: Can be used for washing wounds, surgical sites, or medical instruments (if labeled for irrigation).
• Laboratory & Research Use: Used in medical and pharmaceutical settings for sterile preparations.

4. Dosage & Administration

• Administration Route: IV, IM, or subcutaneous (after mixing with compatible drugs)
• Volume Available: Commonly in 5 mL, 10 mL, 20 mL, 50 mL, 100 mL, 500 mL, and 1000 mL vials or ampoules
• Dilution Guidelines: The amount depends on the specific medication being reconstituted. Always follow the drug manufacturer's instructions.

Important: Never use Sterile Water for Injection alone for direct IV administration-it must be mixed with an appropriate solute to avoid hemolysis (destruction of red blood cells).

5. Side Effects & Risks

• Hemolysis (Red Blood Cell Rupture): If injected directly without solutes
• Electrolyte Imbalance: Excessive use may lead to dilutional hyponatremia
• Infection Risk: If used improperly or stored incorrectly
• Irritation at Injection Site

6. Contraindications & Precautions

• Contraindications:
  • Do not use alone for IV injection (must be mixed with drugs or electrolytes).
  • Do not use if the solution is cloudy, discolored, or contains particulates.
• Precautions:
  • Use under sterile conditions to prevent contamination.
  • Discard any unused portion-do not store opened vials for later use.
  • Be cautious when diluting high-osmolarity drugs to prevent tissue damage.

7. Storage Conditions

• Store at room temperature (25°C).
• Keep in a sterile, sealed container until use.
• Protect from freezing and excessive heat.

8. Conclusion

Sterile Water for Injection is an essential medical diluent used for preparing injectable drugs. It must always be used properly and never injected alone without appropriate additives to prevent serious complications.